S-Acetyl-Glutathione (SAG) is an advanced, and more bioavailable form of glutathione. It’s a tripeptide that’s critical for cellular protection, detoxification, and redox balance. Unlike standard glutathione, SAG’s acetylation enhances its stability and absorption, making it a superior choice for custom dietary supplements for optimizing patient outcomes across a range of health areas.
Clinical Evidence Supports Superior Bioavailability & Efficacy of SAG
SAG’s stability and enhanced absorption make it a standout choice for effective glutathione replenishment.
S-Acetyl-Glutathione, a highly bioavailable form of the master antioxidant glutathione, overcomes conventional glutathione’s poor gastrointestinal absorption through acetylation, which protects it from digestive degradation.
Bioavailability studies confirm SAG achieves significantly higher intracellular glutathione levels than non-acetylated forms, delivering greater therapeutic impact.
For patients with compromised antioxidant defenses, such as those with chronic inflammatory conditions, metabolic disorders, or high toxicant exposure, SAG provides superior results. Preliminary clinical trials indicate reduced oxidative stress markers, while neuroprotective studies suggest potential in reducing neural oxidative damage, offering promise for cognitive health.
Targeted Applications for Patient-Specific Needs
- Oxidative Stress Management: SAG neutralizes free radicals and mitigates oxidative damage, a key driver of chronic diseases like cardiovascular disorders, diabetes, and neurodegenerative conditions.
- Detoxification Support: SAG enhances phase II detoxification in the liver by conjugating toxins for excretion. This is particularly relevant for patients exposed to harmful pollutants and toxins.
- Immune System Optimization: Glutathione is vital for T-cell function and immune modulation. SAG’s ability to replenish glutathione levels supports immune resilience, making it ideal for patients with recurrent infections, autoimmune conditions, or those recovering from acute illness.
- Neuroprotection: Emerging research highlights SAG’s potential to protect neurons from oxidative damage, a factor in Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. For patients with cognitive decline or at risk of neurodegeneration, SAG offers targeted support to support brain health.
- Skin Health and Anti-Aging: SAG’s antioxidant properties combat oxidative stress in dermal tissues, promoting repair and reducing signs of aging.
Start Building Your Personalized S-Acetyl-Glutathione Custom Formula
SAG is a game-changer in custom dietary supplements, offering healthcare practitioners a potent, bioavailable tool to address patient-specific needs for combating oxidative stress, supporting detoxification, strengthening immunity, and protecting neurological and dermal health.
Connect with our experts to know more about getting started to build your personalized SAG formulation.







