NR is one of the most popular ingredients when it comes to improving the mitochondrial health of individuals through custom dietary supplements. When combined with synergistic ingredients like Coq10, MicroPQQ, Acetyl l carnitine, Alpha Lipoic Acid, N acetyl cysteine, D- Ribose, and AKG can improve the overall well-being of your patients in innumerable ways by optimizing cellular energy production.
How does NR, the NAD+ Precursor, affect Mitochondrial Health?
NR, or Nicotinamide riboside chloride, is a Vitamin B3 form that acts as a precursor to NAD+ ( Nicotinamide Adenine Dinucleotide ). It’s a coenzyme necessary to facilitate seamless mitochondrial function. An adequate amount of NAD+ levels in the body ensures adequate ATP synthesis, facilitates cellular repair, improves metabolism, and boosts longevity. Age-related NAD+ decline lowers mitochondrial functioning and maximizes oxidative stress. Therefore, incorporating custom nutraceuticals in your patient’s dietary supplementation regimens enables them to maintain higher NAD+ levels and improve overall health.
300 mg of NR as Daily Dosage: A Case Study for Practitioners
Recent research and clinical trials have found that incorporating 300mg of NR daily in a supplementation regimen can significantly boost mitochondrial function and cellular health of individuals, especially age-related reduction in NAD+ levels.
At the 300mg mark, it strikes the perfect synergy between efficacy and practicality for the patient.
- Not only does it help in elevating NAD+ levels, but also improves mitochondrial oxidative capacity and reduces cellular stress.
- It facilitates energy metabolism by maximizing ATP production and faster synthesis in blood cells.
- It reduces markers of oxidative damage and provides anti-oxidant benefits over a consistent period.
- Also, it leads to better glucose metabolism through improved insulin sensitivity in metabolically challenged patients.
- Lastly, it improves cognitive abilities and physical functioning by boosting mental clarity, lowering fatigue, and maximizing endurance for high-energy exercises and workouts.
Therefore, Nicotinamide riboside chloride (NR) is a foundational ingredient in building custom supplements that target the mitochondrial health of individuals for optimal well-being.
Synergistic Ingredients for Your Mitochondrial Support Formulation
Although NR has substantial benefits in terms of improving mitochondrial health, it can amplify mitochondrial support for your patients when paired with ingredients like –
- Coq10
Coq10 also known as Coenzyme Q10 acts as an electron carrier in the ATP synthesis process and protects against oxidative stress due to its anti-oxidant properties. While NR helps in the availability of NAD+ for electron transport, Coq10 ensures robust flow of electrons within the mitochondrial system for increased ATP production.
- MicroPQQ
MicroPQQ stimulates mitochondrial biogenesis and helps in creating new mitochondria by activating the necessary pathways. Helps in protecting the neurons and boosts cognitive functioning by reducing oxidative stress. While NR helps in optimizing existing mitochondrial functioning, PQQ amplifies cellular energy capacity. This builds more robust mitochondrial networks in the body.
- Acetyl L Carnitine
Helps in transporting fatty acids to the mitochondria for beta-oxidation which is a key energy production mechanism. Helps in crossing the blood-brain barrier and improves cognitive health. When paired with NR, it helps boost mitochondrial fuel utilization and perfectly balances the dependency on NR for energy production.
- Alpha Lipoic Acid
It acts as a universal anti-oxidant that supports glucose metabolism efficiently by acting as a cofactor in the Krebs cycle. When paired with NR, it helps protect the mitochondrial from oxidative damage while NR facilitates NAD+ driven repair mechanisms.
- N-Acetyl Cysteine
It acts as a precursor to glutathione, helps in removing free radicals in the body, supports liver detoxification, and boosts immunity. When paired with NR, it prevents oxidative stress that can affect NAD+ synthesis in the body.
- D- Ribose
It helps in supporting ATP synthesis by acting as a backbone for adenine nucleotides. Best suited for conditions like Chronic fatigue due to significant ATP depletion. When paired with NR, it helps in sustained energy production and retention over longer periods.
- AKG
Helps in supporting energy metabolism and acts as a signaling molecule to reduce inflammation and promote longevity. AKG helps boost the efficiency of the Krebs cycle and maximizes NR’s capabilities in streamlining NAD+ dependent metabolism. Together, they help in keeping the energy production cycle up and running smoothly.
Build Your Synergistic Personalized Mitochondrial Support Formula
Get started with Personalized Nutrients today to build your custom mitochondrial health support formula where you blend NR with these supporting ingredients to enable faster energy production, synthesis, cellular repair, and metabolism, and promote healthy aging.
